segunda-feira, fevereiro 21, 2011

MESA: Só pode ser brincadeira!


Cardiovascular Imaging for Assessing Cardiovascular Risk in Asymptomatic Men Versus Women

The Multi-Ethnic Study of Atherosclerosis (MESA)

Circulation: Cardiovascular Imaging.2011; 4: 8-15






Carotid IMT Measurement

The carotid arteries were evaluated with high-resolution B-mode ultrasonography. Readings were performed centrally at the Department of Radiology, New England Medical Center (Boston, MA). Internal carotid IMT was measured at the level of the carotid bifurcation (common carotid artery bulb and proximal internal carotid artery), and common carotid IMT was measured over a distance of 10 mm proximal to the common carotid bulb. IMT measurement included plaque thickness. Maximal IMT of the internal and common carotid sites was measured as the mean of the maximum IMT of the near and far walls of the right and left sides. A composite z score for overall maximal IMT was created by summing the 2 carotid IMT sites (if both were measured) after standardization (subtraction of the mean and division by the SD of each measure) and then dividing by the SD of the sum. If only 1 of the 2 measures was available, it was used. The z score maximum IMT has a mean of 0 and an SD of 1.
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Para comparar dois métodos de imagem,o mais correto é usar a metodologia mais empregada em ambos.
Veja que salada fizeram com o IMT para comparar com o Cálcio!
Lógico que foi inferior...
Isso me lembra um estudo comparando um Betabloqueador seletivo no pós infarto com outro Betabloqueador. Só que o "outro" era usado em subdose. Advinha quem foi superior?
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