quarta-feira, fevereiro 22, 2012

Disfunção diastólica: Vale a pena acompanhar.

Aqui
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Impact of Progression of Diastolic Dysfunction on Mortality in Patients With Normal Ejection Fraction
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Circulation.
2012; 125: 782-788
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A total of 1065 outpatients were identified (mean±SD age, 67.9±13.9 years; 58% male). Baseline diastolic dysfunction was present in 770 patients (72.3%), with mild being the most prevalent. On follow-up testing (mean±SD, 1.1±0.4 years), 783 patients (73%) had stable, 168 (16%) had worsening, and 114 (11%) had improved baseline diastolic function. Eighty-eight patients (8.3%) had a decrease in left ventricular ejection fraction to <55% and were more likely to have advanced diastolic dysfunction (P=0.002). After a mean±SD follow-up (from the second study) of 1.6±0.8 years, 142 patients (13%) died. On multivariate analysis, a decrease in left ventricular ejection fraction to <55% and any worsening of diastolic function were independently associated with increased risk of mortality . Conclusion—In patients with normal baseline left ventricular ejection fraction, worsening of diastolic function is an independent predictor of mortality. .


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Estudo avalia o valor dos parâmetros diastólicos no seguimento de pacientes com fração de ejeção preservada.
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